Peptide serum · Once a day · Tested against a placebo
NAPE Peptide Hair Serum
For men whose follicles stopped responding — and who aren’t going back to minoxidil.
Five signalling peptides plus Baicapil™ — the complex that cut hair loss by 60.6% and raised hair density by 59.3% in three months, measured against a placebo — in a once-a-day serum with no alcohol and no propylene glycol. One dropper, twenty seconds, dries clear.
- Less hair on the pillow and in the shower.In the Baicapil study, hair loss measured −60.6% at three months against day one — on the studied lotion, at 3%.
- A crown that stops showing scalp under overhead light.Hair density in the same study: +59.3% at three months. Judge yours against a day-one photo from above, in the same light.
- Temples and a hairline that look less see-through.Five signalling peptides — copies of the growth-factor family your follicles used when they were making thick hair — in a lecithin base built to reach the scalp, not sit on the hair.
- A scalp that isn’t itching by six in the evening.No alcohol, no propylene glycol — the two things that made minoxidil itch and crust. Eucalyptus leaf extract for comfort.
- Once a day. Twenty seconds. Not twice a day, forever.One dropper on a dry scalp, worked in with your fingertips. Dries clear in about a minute — nothing on the pillow, nothing to wash out.
If your hair hasn’t changed by day ninety, email us and we refund what you paid.
For external use only. Avoid contact with eyes. Patch test before first use. Discontinue if irritation occurs. Sunburn alert: this product contains an alpha hydroxy acid that may increase sensitivity to the sun. Not for use by athletes subject to anti-doping testing. Not recommended during pregnancy or breastfeeding, or with a history of hormone-sensitive cancer - ask your doctor.
Tested against a placebo. Not a questionnaire.
NAPE is built around Baicapil™ — a complex of Scutellaria baicalensis root, soy germ and wheat germ. Its maker, Provital, tested it on 61 volunteers, men and women aged 18–60, for six months: half on a 3% Baicapil lotion, half on a placebo lotion. Hair loss and density were measured, not self-reported.
61 people, six months
Half used a lotion with 3% Baicapil, half used a placebo lotion — the comparison most products in this category never run.
Hair loss: −60.6% at three months
Measured against day one, in the Baicapil group. In plain terms: less of it on the pillow and in the shower.
Hair density: +59.3% at three months
Measured against day one, in the Baicapil group. In plain terms: a crown that photographs closer to the way it used to.
Growth phase: +68.6% at six months
The anagen-to-telogen ratio — the share of hair in its growth phase — measured at six months. That is the number behind the fuller-looking crown. Supplier study; results belong to the studied complex at its studied level.
Figures are from Provital’s study of Baicapil™ at 3%, on the studied lotion, not NAPE as a finished product. NAPE is a cosmetic product and is not intended to treat, prevent or cure any condition.
Minoxidil pushes blood into the follicle. Peptides talk to it.
A follicle producing thin, short, see-through hair hasn’t died. It has stopped receiving the signals that kept it in its growth phase — and started listening to DHT instead. Minoxidil works around that by dilating blood vessels, twice a day, forever. NAPE takes the other route: it puts the signals back.
One dropper to the crown. Once a day.
Step 1 · Signal Five signalling peptides
Lab-made copies of the growth-factor family your follicles used when they were making thick hair — IGF, FGF, VEGF, KGF. Water-soluble, carried in a lecithin base built to reach the scalp, not sit on the hair.
Step 2 · Growth phase Baicapil™ — the studied complex
Scutellaria root, soy germ and wheat germ. In the six-month placebo trial it shifted the anagen-to-telogen ratio — the share of hair in the growth phase — by +68.6%.
Step 3 · DHT Saw palmetto and baicalin
The two plant extracts studied for how they interact with the androgen pathway that miniaturises follicles at the crown and temples — the pattern almost every man on this page recognises.
Step 4 · Scalp No alcohol. No propylene glycol.
The two ingredients that made minoxidil itch and crust are not in the bottle. Eucalyptus leaf extract for a scalp that isn’t tight by evening. Dries clear in about a minute.
What men tend to notice first — and when
Hair runs on a ninety-day cycle. Nothing topical changes that, which is why the course is ninety days and so is the guarantee. Take a photo of the crown from above on day one, in the light where you first noticed it.
Weeks 1–2
The scalp
No itch by evening, no crust in the morning. Hair that isn’t wet after applying. This is the part that decides whether you’re still using it in week six.
Weeks 3–6
The pillow and the shower
Less of it left behind. In the Baicapil study, hair loss measured −60.6% at three months against day one.
Weeks 6–10
The hand
Hair that feels heavier between your fingers. Fine hairs at the temples and crown that are easier to find.
Week 12
The photo
The crown from above, the hairline from the front, judged against your day-one photo in the same light. Density in the study: +59.3% at three months.
One full dropper. Not a third of one.
Both our bottle and the cheap ones hold 30 ml. The difference is what you are told to do with it. A full dropper parted across four or five sections of scalp uses about a millilitre a day, which is why a bottle is a month.
A 30 ml bottle sold as a three-month supply is the same glass with a third of the dose. That is where the low price comes from, and it is why so many people conclude that peptide serums do not work.
1 ml a day
A full dropper, once daily. 30 ml lasts thirty days, which is what a month of use actually costs.0.33 ml a day
A third of a dropper across an entire scalp. The bottle lasts longer because far less of it reaches you.Twenty seconds, once a day. Nothing to wash out.
On a dry or towel-dried scalp — the skin, not the lengths. Morning or evening, whichever you’ll actually keep.
1
Photograph it first
Before the first application, take a photo of the crown from above and the hairline from the front, in the light where you first noticed it. In ninety days it’s the only comparison that will tell you anything.
2
Part and apply
Draw one dropper. Part the hair over the crown or the corners and lay the serum onto the scalp in a few lines — the skin, not the lengths.
3
Twenty seconds, then leave it
Work it in with your fingertips for about twenty seconds. Don’t rinse. It dries clear in about a minute and leaves nothing on the pillow.
You didn’t quit minoxidil because it failed.
Published adherence data says most men stop around month three — the month the drug is working hardest. Not because it stopped working: because it was twice a day, forever, and it left the hair crusted and the scalp itching.
So the routine is the thing we built first — once a day, dries clear, nothing to wash out — and the guarantee runs ninety days, not thirty. If minoxidil is working for you, stay on it. This is for the men it didn’t work out for.
Against what you’ve probably already tried
Most men arrive here having used one of these. This is what each one asks of you — including the rows where we don’t win.
See the 90-day courseComparisons describe the category, not any named brand. Re-check each row against current labelling whenever this page is edited.
| NAPEOnce-a-day peptide serum | Minoxidil topical | Prescription tablet | A 30 ml serum sold as 3 months | |
|---|---|---|---|---|
| Daily routine | 20 seconds, once | Twice a day, every day | One tablet | Once |
| After applying | Dries clear in about a minute | Wet, greasy or crusted hair | n/a | Varies |
| Alcohol or propylene glycol in the base | Neither | Usually both — the itch | n/a | Often |
| How it works | Peptide signalling + growth-phase complex | Vasodilation | Blocks DHT throughout the body | Varies |
| Tested against a placebo | Key complex — 61 people, 6 months | Yes — drug trials | Yes — drug trials | Rarely |
| Needs a prescription | No | No | Yes | No |
| What one 30 ml bottle covers | 30 days at one dropper | About 30 days | n/a | Sold as 90 days — a third of a dropper |
| Subscription | None — one-time purchase | Retailer dependent | Repeat prescription | Usually auto-ship |
| If it doesn’t work for you | 90 days, one email, full refund | Retailer policy | None | Varies |
Where you notice it first
Pick the area you see most. The routine is the same everywhere; what to watch for is slightly different.
Under overhead light
- Light catches skin at the crown
- The barber’s mirror shows more than yours does
- Styling stops covering it
- Fine in most light, obvious in one
Where to apply
- Photograph the crown from above on day one
- Part in a star across the crown, four or five lines
- One dropper, twenty seconds, once a day
- Same photo, same light, on day 30, 60 and 90
By week twelve
- Less of it on the pillow and in the shower
- Hair that feels heavier in the hand
- Coverage that survives styling
- A crown photo that reads closer to day one
The corners
- The temples look deeper than in last year’s photos
- Fine hairs at the front are harder to find
- A cap sits differently
- You’ve started combing it forward
Where to apply
- Photograph the hairline from the front, hair pushed back
- Trace the serum along the front and into each corner
- Work in with fingertips for twenty seconds
- Don’t rinse — it dries clear before you leave the house
By week twelve
- Less on the pillow in the morning
- Corners that photograph closer to day one
- Fine hairs at the front that are easier to find
- A routine you’re still doing
No one spot
- Hair on the pillow and the collar
- More in the shower after every wash
- The whole top looks thinner under overhead light
- No one spot, just less of everything
Where to apply
- Photograph the crown and the hairline on day one
- Part in four or five sections across the top
- One dropper spread across them, twenty seconds
- Once a day, dry scalp, don’t rinse
By week twelve
- Less of it left in the shower
- Hair that feels heavier in the hand
- A top that reads fuller under the same light
- A photo that holds steady against day one
The part
- The line looks broader than it used to
- Volume at the roots is gone by lunchtime
- Hair feels thinner in the hand
- The part in photos is what bothers you most
Where to apply
- Photograph the part straight down on day one
- Lay the serum along the part, then one line either side
- Twenty seconds with fingertips
- Same photo, same light, every thirty days
By week twelve
- Hair that feels thicker between your fingers
- Roots that hold through the day
- A part that photographs closer to the way it used to
- Less in the shower
Ninety days, or your money back.
Use the full three-bottle course. If your hair hasn’t changed by day ninety, email us and we refund what you paid. One email. No forms, no restocking fee.
Ninety days isn’t a round number chosen because it sounds generous. It’s the shortest honest window in which anything topical can be judged on hair — and it’s the window the Baicapil study itself reported at.
- Ninety days, not thirty. Long enough to actually judge it.
- One email, no questions. No forms, no restocking fee.
- Nothing to cancel. Every pack is a one-time purchase. There is no subscription to unwind.
The full terms are in our Refund Policy. In short: claims are made by email, and the guarantee covers each customer once. Faulty, damaged or incorrect orders are handled separately and are not counted as a guarantee claim.
What’s in the bottle, and what each part is there for
Four things, in the order they matter to a follicle that has stopped responding.
Five signalling peptides
The part of the formula the name comes from. Copies of the growth-factor family — IGF, FGF, VEGF, KGF — that follicles use when they are making thick hair. Water-soluble, which is why the base can stay free of alcohol and still carry them to the scalp.
sh-Polypeptide-1 / -9 / -11, sh-Oligopeptide-2 / -10Baicapil™ — the studied complex
Scutellaria baicalensis root, soy germ and wheat germ. The reason there is a placebo-controlled study behind this product at all: 61 people, six months, hair loss −60.6% and density +59.3% at three months, growth-phase ratio +68.6% at six.
Scutellaria baicalensis root extract, Glycine soja germ extract, Triticum vulgare germ extractSaw palmetto and baicalin
The two plant extracts studied for how they interact with the androgen pathway that miniaturises follicles at the crown and temples.
Serenoa repens extract, Scutellaria baicalensis root extractThe base
Water, glycerin, lecithin, propanediol. No alcohol, no propylene glycol, no fragrance — the things that made minoxidil itch and crust. Eucalyptus leaf extract for a scalp that isn’t tight by evening. Dries clear in about a minute.
Water, Glycerin, Lecithin, Propanediol, Eucalyptus globulus leaf extractWhat's in it, one at a time
Five signalling peptides
sh-Polypeptide-1, -9, -11 · sh-Oligopeptide-2, -10
- The growth-factor family: IGF, FGF, VEGF, KGF — the signals follicles use in their growth phase
- Named on the label: All five, in order, on the bottle
- Carried to the scalp: Lecithin base, no alcohol needed
This is the part that talks to the follicle instead of pushing blood past it.
Baicapil™
Scutellaria baicalensis root · soy germ · wheat germ
- 61 people: Men and women, 18–60, six months, half on a placebo lotion
- Hair loss: −60.6% at three months against day one, in the Baicapil group
- Hair density: +59.3% at three months against day one, in the Baicapil group
- Growth phase: anagen-to-telogen ratio +68.6% at six months
The reason this page can show you a study instead of a testimonial. Supplier study, at 3%. The results belong to the studied complex, not to NAPE.
Saw palmetto
Serenoa repens extract
- Studied in men: Published human data in androgenetic hair loss
- The pathway: The androgen route that miniaturises follicles at the crown and temples
- On the label: Listed in full, in order
The botanical this audience already knows by name — here as a topical, not a tablet.
Eucalyptus leaf extract
Eucalyptus globulus
- Scalp comfort: For a scalp that isn’t tight or itching by the evening
- Studied on people: For scalp condition and hair shine
- Every day: Comfort is what keeps a daily serum daily
A serum you use for ninety days has to feel like nothing. This is the ingredient that does that job.
The base
Water · glycerin · lecithin · propanediol
- Dries clear: In about a minute, no residue
- No alcohol: Nothing to dry the scalp out
- No propylene glycol, no fragrance: The two things that made minoxidil itch
The base is most of the bottle, and it’s most of the reason men keep using it.
Research described here was conducted on individual ingredients as studied, not on the finished NAPE formula. NAPE is a cosmetic product and is not intended to treat, prevent or cure any condition.
What's not in it
A serum sits on your scalp every day for months. What's been left out of it matters as much as what went in.
Formulation attributes confirmed by the manufacturer of the formula.
The full list. Nothing held back.
Every ingredient in the bottle, in the order it appears on the label. Most brands in this category publish a summary. This is the whole thing.
Ingredients
Water, Glycerin, Lecithin, Propanediol, Arginine, Caprylyl Glycol, Citric Acid, Eucalyptus Globulus Leaf Extract, Tocopherol, sh-Polypeptide-11, sh-Polypeptide-1, sh-Oligopeptide-2, sh-Oligopeptide-10, sh-Polypeptide-9, Lactic Acid, Glycine Soja (Soybean) Germ Extract, Triticum Vulgare (Wheat) Germ Extract, Scutellaria Baicalensis Root Extract, Sodium Benzoate, Gluconolactone, Calcium Gluconate, Potassium Sorbate, Rosmarinus Officinalis (Rosemary) Extract, Xanthan Gum, Sodium Gluconate, Serenoa Repens (Saw Palmetto) Extract
What the five peptide codes actually are
| On the label | Protein | UniProt |
|---|---|---|
| sh-Polypeptide-1 | bFGF / FGF-2 | P09038 |
| sh-Polypeptide-9 | VEGF-A | P15692 |
| sh-Polypeptide-11 | aFGF / FGF-1 | P05230 |
| sh-Oligopeptide-2 | IGF-1 | P05019 |
| sh-Oligopeptide-10 | CCL2 / MCP-1 | P13500 |
Peptides are listed on labels by code, which tells you nothing. These are the proteins behind the codes, with their UniProt accession numbers so you can look each one up yourself.
Ingredient list as supplied by the manufacturer. NAPE is a cosmetic product and is not intended to treat, prevent or cure any condition.
The questions that actually stop people
I tried minoxidil and quit. Why would this be different?
Because the reason most men quit minoxidil isn’t that it failed — it’s twice a day, forever, plus the itch and the crust from the alcohol and propylene glycol base. NAPE is once a day, dries clear in about a minute, and has neither in it. It also works by a different route: peptide signalling and a growth-phase complex, not vasodilation. If minoxidil is working for you, stay on it.
How long until I notice something?
The scalp first — no itch by evening — within the first couple of weeks. Less on the pillow and in the shower around weeks three to six. Hair that feels heavier in the hand by weeks six to ten. The crown and hairline are a twelve-week photo, not a mirror check. Months, not weeks.
What exactly does the 90-day guarantee cover?
The full amount you paid. Use the three-bottle course. If your hair hasn’t changed by day ninety, email us and we refund you — one email, no forms, no restocking fee.
Why three bottles?
Because one is a month, and a month can’t tell you anything about hair. Ninety days is the shortest window you can judge it in — it’s the window the guarantee covers, and the one the Baicapil study reported at.
Is this minoxidil?
No, and it doesn’t contain it. It’s a peptide scalp serum applied once a day, with no alcohol and no propylene glycol in the base — so it dries clear rather than leaving hair wet.
Is it for men or women?
It was built for men who noticed it at the crown or the temples — most of the men who find us are over fifty-five and have already tried minoxidil. Women use it too; the routine and the guarantee are the same.
Do I need to keep using it?
Yes. That’s true of every topical in this category, minoxidil included. It’s a daily product, which is why it’s built to be easy to keep: once a day, twenty seconds, dries clear.
Is this a subscription?
No. Every pack is a one-time purchase — you are charged once, nothing renews, and there is nothing to cancel. When you run out, you decide whether to buy again.
Will it cause the shedding phase people talk about?
That effect is most associated with starting certain drug topicals. It isn’t something we’d expect from a cosmetic serum, and it isn’t something the Baicapil study reported. If you notice anything unusual in the first weeks, stop and email us.
Will it do anything where my scalp is already smooth?
Probably not in those places — ours or anyone else’s. It’s made for hair that’s thinning while there’s still fine hair in the area. If there is, that’s where to apply it.
Who should not use this?
It contains an alpha hydroxy acid, so use sun protection on any exposed scalp. If you have a history of hormone-sensitive cancer or are subject to anti-doping testing, ask your doctor first. Not recommended during pregnancy or breastfeeding.
Why is it more expensive than the serums I see on Instagram?
Dose. A 30 ml bottle sold as a three-month supply is the same glass with a third of the daily amount. Ours is one dropper a day, so a bottle is a month — and the price per month is what it costs to actually use it.
Where is it made?
Made in the USA. The full ingredient list is printed on the bottle, in order, and on this page.
Ninety days, and you’ll know
Three bottles is the course. Take the photo today, one dropper every day, and judge it in three months against that photo — not against memory.
What this is not. It is not a drug and it is not a transplant. Where a scalp has gone smooth there’s nothing for a topical to do — ours or anyone else’s. It’s made for hair that’s thinning while there’s still fine hair in the area.