Peptide hair serum
One dropper. Once a day. That's the whole routine.
Twenty seconds on a dry or towel-dried scalp. Dries clear — no crust, no grease, nothing to rinse out. Twenty-six ingredients, printed on the front in order. Ninety-day money-back guarantee.
- Manufactured in the USA
- 90-day money-back
- Free US shipping
Where do you notice it?
Thinning runs through the same three stages everywhere on the scalp. Only the order changes - and where you notice it first is rarely where it started.
Crown
The spot that only shows up in photographs, under a light, from above.
Hairline & temples
The corners retreating a few millimetres a year until the parting sits somewhere new.
Part line
The line that reads wider than it did last year, and a ponytail that feels thinner in the hand.
All-over shedding
Nothing localised - just more hair in the drain, the brush and the pillow than there used to be.
Five peptides and four botanical extracts
What each part of the formula is there to do - and, where the evidence does not support a growth claim, what it is not there to do.
Five signalling peptides
sh-Polypeptide-1 is bFGF and sh-Oligopeptide-2 is IGF-1 - growth-factor peptides that support the appearance of thicker, fuller hair. We name them by the proteins they actually correspond to, which sounds like a low bar until you check what else in this category gets it wrong.
sh-Polypeptide-1 / -9 / -11, sh-Oligopeptide-2 / -10Amino acid support
Arginine, an amino acid the hair shaft is partly built from, supports hair strength and helps hair look and feel healthier through the length.
ArginineBotanical conditioning
Eucalyptus extract supports the scalp barrier and adds shine and body to the hair itself. This is a comfort-and-condition ingredient rather than a growth one, and we would rather tell you that than let it sit on the page implying otherwise.
Eucalyptus globulus leaf extractSaw palmetto for fullness
The one ingredient in the formula with published human results in pattern hair loss. It acts on the enzyme behind DHT and helps maintain the appearance of fuller, thicker hair.
Serenoa repens extractThree mechanisms, not three of the same thing
Saw palmetto works on the enzyme that converts testosterone into DHT, the hormone that shrinks a follicle a little more with every cycle until the hair it makes is too fine to count. This is the one active in the formula with human data in androgenetic hair loss - and it is worth saying plainly that the study was open-label, uncontrolled, and ran on a multi-ingredient product.
Baicalin, from Scutellaria baicalensis root, is an androgen receptor antagonist rather than another enzyme blocker. Lowering the hormone and dulling the receptor that responds to it are two different jobs. Most serums in this category stack three actives that all do the first one and call it a system.
Soy germ extract addresses perifollicular inflammation - the low-grade irritation that keeps a follicle from committing to a full growth phase. Preclinical evidence only, and we are not going to pretend otherwise.
Five signalling peptides corresponding to bFGF, VEGF-A, aFGF, IGF-1 and CCL2. We name the proteins correctly, which sounds like a low bar until you check what the competitor advertorials in this category call them - four of the five are misidentified in the ones we looked at.
IGF-1 is about 7.6 kilodaltons. VEGF-A is about 45. The stratum corneum exists specifically to stop molecules that size. So the lecithin carrier, the lactic acid and gluconolactone pair that clears the follicular opening, and the alcohol-free propanediol and glycerin base are not filler around the actives - they are the reason there is any point having actives at all.
One bottle cannot answer the question
A hair cycle takes about ninety days. Every serious study in this category runs ninety days or longer, because that is how long it takes a follicle to finish what it started. Thirty days tells you nothing - which is why the three-bottle pack is the honest default, not the upsell.
One bottle
30 days
$79
$79 per bottle
- Enough to learn the routine
- Not enough to judge the result
- 90-day guarantee
Three bottles
90 days - a full hair cycle
$150
$50 per bottle, save $87
- The minimum course the biology needs
- Save $87 against buying singles
- One-time purchase, nothing renews
- 90-day guarantee
Six bottles
180 days
$258
$43 per bottle, save $216
- Two full cycles, for slow responders
- Lowest price per bottle
- One-time purchase, nothing renews
- 90-day guarantee
Every pack is a one-time purchase. Nothing renews, there is nothing to cancel, and every order carries the 90-day money-back guarantee.
What is actually inside
Twenty-six ingredients, printed in full on the bottle rather than hidden behind a proprietary blend. Five of them are signalling peptides, and we name the proteins they correspond to - most of this category gets that mapping wrong, including some of the brands charging three times as much.
The rest of the formula is the part nobody advertises: a lecithin carrier, a lactic acid and gluconolactone pair, propanediol and glycerin with no alcohol and no PG. Growth-factor peptides are large molecules and the scalp exists to keep large molecules out. Delivery is not an excipient here. It is the product.
Works on the enzyme that makes DHT. The strongest evidence in the formula, and the only ingredient here with human data in androgenetic hair loss. The often-quoted 74% figure refers to terminal hairs specifically; total hair count in the same study rose about 5%.
Human AGA dataBasic fibroblast growth factor. Extends the growth phase and supports the dermal papilla. Human studies used injection or microneedling rather than a topical serum, which is why the carrier system matters as much as the peptide.
Animal plus human, not topicalInsulin-like growth factor 1. In human hair-follicle organ culture it keeps follicles in anagen instead of letting them slide into rest. About 7.6 kilodaltons, which is why delivery is the whole problem.
Human tissue cultureVascular endothelial growth factor. Associated with perifollicular blood supply. Preclinical only - the evidence is in mice and there is no human topical trial.
Preclinical onlyAcidic fibroblast growth factor. Included as part of the growth-factor set. We will be straight about this one: the published work found no effect on fibre elongation.
No hair evidenceAn androgen receptor antagonist - it dulls the receptor rather than blocking the enzyme, which is a genuinely different mechanism from saw palmetto. Preclinical evidence only.
Preclinical onlyA phospholipid carrier, an acid pair that clears the follicular opening, and a humectant base with no alcohol and no propylene glycol. Every peptide above is far too large to cross the stratum corneum unassisted, so this is not the boring half of the formula.
The part nobody advertisesWhat is not in it
A hair serum sits on your scalp every day for months. What has been left out matters as much as what went in.
Formulation attributes confirmed by the manufacturer of the formula.
Where the evidence actually stands
Every brand in this category says clinically proven. Almost none of them will tell you which ingredient the trial was on, what it was compared against, or whether it was ever tested on a human scalp. Here is ours, sorted honestly - strongest at the top.
Human data, in this condition
Saw palmetto is the only ingredient in NAPE with published results in androgenetic hair loss in people. It is real evidence and it is also open-label, uncontrolled, and run on a multi-ingredient product - so it supports the mechanism, not a guarantee.
Wessagowit et al., Australas J Dermatol 2016; 57(3):e76-82. Evron et al., systematic review, 2020.
Human tissue, not yet a human trial
IGF-1's effect on keeping follicles in their growth phase was shown in cultured human hair follicles. That is human biology, but it is not the same as a trial on a scalp.
Philpott et al., J Invest Dermatol 1994; 102(6):857-61. Panchaprateep & Asawanonda, Exp Dermatol 2014; 23(3):216-18.
Human results, but not from a bottle
bFGF has both animal and human results behind it. The human work delivered it by injection or microneedling, not as a topical serum - which is exactly why we built the formula around a carrier system rather than around the peptide list.
Lin et al., BioMed Res Int 2015; 2015:730139. Liu et al., J Cosmet Dermatol 2022; 21(9):4053-59.
Promising, in animals and cells only
VEGF-A, baicalin, soy germ and arginine all sit here. Good mechanistic reasoning, published work behind each one, and no human topical trial for any of them. We include them because the mechanisms are complementary, not because they are proven on a human head.
Yano et al., J Clin Invest 2001; 107(4):409-17. Kim et al., Planta Med 2014; 80(2-3):153-58. Youssef et al., J Med Food 2025; 28(1):75-86.
Ninety days, or your money back
If your hair has not changed in ninety days, email us and we refund what you paid. We ask for ninety days because that is what a hair cycle takes - it is the shortest window in which a topical can honestly be judged.
- One-time purchase, nothing renews
- Free US shipping
- Manufactured in the USA
- 26 ingredients, all printed on the bottle
Guarantee terms: 90-day money-back guarantee, claims by email, one claim per customer - full terms in our Refund Policy. For external use only. Patch test before first use. Keep out of reach of children. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual results vary and depend on the cause and stage of thinning.